Pau studied Human Biology at the Universitat Pompeu Fabra, Barcelona, before moving to Oxford, London and the Technical University of Denmark where he obtained his PhD in Computational Biology.
He then received a postdoctoral fellowship from the Helen Hay Whitney Foundation to pursue his postdoctoral studies at the Koch Institute for Integrative Cancer Research at MIT. After securing a K99/R00 Pathway to Independence award from NIH/NCI, he established his lab at the University of Cambridge – CRUK Cambridge Institute in 2020.
I really enjoy thinking deeply about research questions and how by doing so we can contribute towards improving disease outcomes.
Ab initio protein / peptide / drug design
“Imagination is more important than knowledge. For knowledge is limited, whereas imagination embraces the entire world, stimulating progress, giving birth to evolution.” - Albert Einstein
This will never work / You can’t do it
Mihkel is a postdoctoral research fellow who is interested in (unravelling and targeting) protein signalling networks. His PhD work in the University of Tartu in Estonia was on protein phosphorylation in yeast cell cycle. He then joined the Institute of Cancer Research in London to characterise motif-mediated protein-protein interactions in a high-throughput manner. He joined Pau Creixell’s lab with a Horizon Europe Guarantee MSCA postdoctoral fellowship to investigate the therapeutic potential of targeting dynamic protein-protein interactions.
In my free time I enjoy hiking and exploring new areas
Short linear motifs in signal processing
"Intelligence is knowing the right answer. Wisdom is knowing when to say it." - Tim Fargo
Unmotivated people, mushy peas
Gerard is a postdoctoral researcher interested in protein design and cancer signalling networks. During his PhD he studied membrane proteins from a biophysical point of view, using molecular biology and biochemistry tools. He spent some time at the Weizmann Institute of Science, where he worked on membrane protein design projects regarding apoptosis. He has now joined Pau Creixell’s lab at the CRUK-Cambridge Institute.
When I have free time I like to cook. Cooking, like science, is about following protocols. Sometimes it works out well, but other times it doesn't.
Membrane proteins. Nice figure design.
“Science is not about building a body of known “facts”. It is a method for asking awkward questions and subjecting them to a reality-check, thus avoiding the human tendency to believe whatever makes us feel good” – Terry Pratchett
Cold weather / dichotomies
Thinking outside the box.
Mingxuan has recently completed studying Chemistry with Molecular Physics Master’s Program at Imperial College London, where he specialised in robotic chemistry and computational chemistry for drug design. He came top in the year – the best chemistry student in the whole of London, 2021. He is now at Cambridge Universtiy working towards his PhD in Pau Creixell’s group.
The Medicine Buddha Pagoda in Nanjing makes me reminisce of my home far, far away. Its spirit also reminds me to dedicate myself to improving medical approaches to ease suffering in this world.
Molecular biophysics and experimental drug discovery
I cannot stand long beans, especially if they are undercooked. Too rubbery!
Like Naruto, Ramen is my soul as well.
Cancer signaling explorer
"Life is not easy for any of us. But so what? We must have perseverance and above all confidence in ourselves. We must believe that we are gifted with something and that this thing must be achieved." - Marie Curie
Luis is a biologist, geneticist and bioinformatician from Costa Rica. His past research was focused on human genetics, DNA repair and radiation oncology. His current research as a PhD student in the Creixell Lab is focused on the molecular evolution of tyrosine kinases. Moreover, he combines high-throughput biochemistry and structural bioinformatics in order to design less toxic and more efficient therapeutic hits to target oncogenic tyrosine kinases in paediatric brain tumours. He was awarded a PhD fellowship from the Board of Trustees of the Boehringer Ingelheim Fonds (BIF) in 2022 and became an Associate Member of the Royal Society of Biology in 2023.
I am passionate about history, architecture and art. Castles are fascinating and remind me that every kingdom must one day come to an end.
Structural bioinformatics and protein biochemistry
Try until you achieve it
Waking up early
“We are what we repeatedly do. Excellence, then is not an act but a habit” - Will Durant (The Story of Philosophy: The Lives and Opinions of the World’s Greatest Philosophers)
Amelia is a PhD student who graduated from her Bsc in Biochemistry from the University of Bath. She completed an industrial placement at the Cancer Research UK AstraZencea antibody alliance lab where she had a fantastic time developing a biological PROTAC. Now she is interested in how understanding protein-protein interactions in the Creixell lab can be used to design targeted therapeutics.
Swimming, running, cycling
Smile and the world smiles with you
If you fold a piece of paper 32 times it will reach the moon
The same water that softens pasta hardens an egg. It’s not about your environment that matters, its how you react to it.
JJ attained his BSc from Nanyang Technological University in Singapore, where his thesis involved the computational design of stapled peptides for PPI inhibition. His work with Dr Chandra Verma at the Bioinformatics Institute, A*STAR then led him into the field of protein kinase biochemistry. He received an A*STAR scholarship to pursue his PhD with the Creixell lab and is looking to reconcile the biochemistry of kinases with their signalling effects as well as engineer new functional proteins for their study.
Badminton is a lot like science; you keep hitting back at whatever unexpected shots thrown your way until a result is obtained.
Computational biophysics, protein dynamics
"But nature did not deem it her business to make the discovery of her laws easy for us" — Albert Einstein "If you torture the data long enough, it will confess" — Ronald Coase
Open-mindedness "Science at its best is an open-minded method of inquiry, not a belief system" – Rupert Sheldrake
Greta has two master’s degrees, from ETH Zurich, Switzerland, one in Chemistry and one in Pharmaceutical Science. She worked in IBM Research Europe on toxicity prediction using deep neural networks and at F. Hoffmann-La Roche in Basel, Switzerland. Her main expertises lie in computational chemistry and protein chemistry as well as machine learning.
In my free time, I love baking and sharing the new creations with the lab members
Science usually does not work the way you want
"Power is gained by sharing knowledge, not hoarding it" – Dale Carnegie
"Knowledge isn’t power until it is applied" – Dale Carnegie
Former MSci student then research assistant; next step as a PhD student at Harvard University
Teresa is a research assistant who recently graduated from her BA and MSci in the Biochemistry Department in Cambridge. Next, she was excited to perform high-throughput biochemical techniques to explore protein-protein interactions in the Creixell lab.
I love sailing. Out on the open ocean, you are a free spirit. In science, the possibilities and pathways can also seem endless, so that's why both of my passions are combined in this icon.
Creating figures or powerpoints (I wouldn’t say I am particularly good at it, but I love spending time on that and improve)
“The world belongs to the brave” – Eva zu Beck
This is our family dog, Jester, a Border Collie.
“How wonderful it is that nobody need wait a single moment before starting to improve the world” – Anne Frank
“The [person] who views the world at 50 the same as [they] did at 20 has wasted 30 years of [their] life” – Muhammad Ali
“...deprived of every right, exposed to every insult, condemned to certain death, but we still possess one power, and we must defend it with all our strength for it is the last – the power to refuse our consent” – Steinlauf
*Some icons created by Javier Cabezas, Creative Mania Alina Oleynik InonMark Stephen Plaster for the Noun Project